Application of Information Science and Technology in Chemical Research

Computational Chemistry: Modeling the Molecular World Modern chemistry relies on software to simulate atomic behavior, replacing costly and time-consuming experiments. Key advancements include: Quantum Chemistry Software: Tools like Gaussian calculate electron behavior to predict molecular stability and reactivity . Molecular Read more…


Decrease in the matrix enhancement effect on pesticides analysis with GC-MS using new types of solid-phase extraction column

What Is the Matrix Enhancement Effect? Matrix effects arise when non-target compounds (e.g., pigments, sugars, or fatty acids) in a sample alter the ionization efficiency of pesticides during GC-MS analysis. For example: False Positives: Matrix components may mimic pesticide signals. Read more…


POLARIZATION-BASEDAFFINITY ASSAYS

Battling Bacterial Infections Pseudomonas aeruginosa, a deadly antibiotic-resistant pathogen, uses lectins like LecA and LecB to attach to host cells. FP assays have been pivotal in screening inhibitors that block these interactions: LecA: Requires 10–15 µM protein due to low-affinity Read more…


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